During the 2022 Russian invasion of Ukraine, the brigade destroyed the elite 4th Guards Tank Division of the Russian Federation in the Battle of Trotstianets after it had been overextended and undersupplied due to partisan resistance in its area of operations.
By September 2022, the brigade participated in the Kharkov Oblast counteroffensive specifically moving into the Izium axis against the Operational Group of Russian Forces Izium's vulnerable left flank. The Russian Ministry of Defense announced that Russian forces in the Izium region were "pulled out" to reinforce the Donbas. Following this, the city's mayor, Valeriy Marchenko, stated during a September 10th interview that "Izium was liberated today."
In October 2022 the brigade spearheaded a successful Ukrainian counteroffensive during the Battle of Bakmut.
